Recurrent Keratoacanthoma

نویسندگان
چکیده

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Keratoacanthoma and Keratoacanthoma-Like Squamous Cell Carcinoma

Differential diagnosis between keratoacanthoma (KA) and squamous cell carcinoma (SCC) is difficult due to their similarities. The mechanisms that drive their distinct biological behavior are poorly understood. To investigate whether the assessment of microvessel density (MVD) could be helpful in KA and SCC differential diagnosis and to gain insight into the pathogenesis of KA-like neoplasms, we...

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Conjunctival keratoacanthoma.

Keratoacanthoma generally occurs on the skin; it is rarely found in the conjunctiva. A case of a 34-year-old woman with a rapidly growing conjunctival mass is reported. The tumor was excised with a safety margin to exclude squamous cell carcinoma. Histopathologically it was crateriform and consistent with atypical keratoacanthoma. There has been no recurrence in 2 years of follow-up. Conjunctiv...

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Sporotrichosis Mimicking Keratoacanthoma

A 73-year-old female presented with a tumor in the frontal region, which had been noticed for the last 3 months (Figure 1, Figure 2). The patient observed a papule similar to a mosquito bite that grew to become tumoral. Incisional biopsy was performed and the lesion partially regressed over the next 30 days, although not treated (Figure 3). Histopathology revealed pseudocarcinomatous hyperplasi...

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Management of Keratoacanthoma

Keratoacanthoma is a tumor that is seen on a regular basis in a dermatologic and dermato-oncologic practice. The accurate management of this tumor is the biggest challenge. Many treatment options are available. In this review, we summarize the clinical and histological features of this not uncommon tumor. We review the current management with an emphasis on treatment.

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Keratoacanthoma of the Lip

The PI3K-PTEN-mTOR is one of the most important pathways involved in cancer development and progression; however, its role in keratoacanthoma (KA) is poorly understood. In this study, we investigated the activation of key proteins in the PI3K-mTOR pathway in lip KA. We analyzed the activation of the PI3K-PTEN-mTOR pathway using human tumor samples stained for well-established protein markers in...

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ژورنال

عنوان ژورنال: SKIN The Journal of Cutaneous Medicine

سال: 2020

ISSN: 2574-1624

DOI: 10.25251/skin.4.4.17